*For correspondence: musa.karadag@igdir.edu.tr
Musa Karadag: https://orcid.org/0000-0003-2498-3403 Mehmet Firat Baran: https://orcid.org/0000-0001-8133-6670 Kadir Sinan Aslan: https://orcid.org/0000-0003-4564-1285 Mehmet Tevfik Adican: https://orcid.org/0000-0001-7733-9676
This study was conducted to determine the phenolic compound profile of Rhus coriaria L. (sumac) and to investigate the potential of these components for developing value-added products in the cosmetic, health, and food industries. Sumac, which holds an important place among medicinal and aromatic plants, possesses strong antioxidant, antimicrobial, and anti-inflammatory effects thanks to its rich content of phenolic acids, flavonoids, and organic compounds. In this study, the phenolic content of ethanol-water (80:20, v/v) extracts obtained from sumac fruit samples was analyzed using high-performance liquid chromatography (HPLC-DAD). A total of 10 phenolic compounds were identified as a result of the analysis. The compound with the highest concentration was gallic acid (5212.65 ng/µL), followed by ferulic acid (671.76 ng/µL), ascorbic acid (255.23 ng/µL), protocatechuic acid (111.67 ng/µL), and o-coumaric acid (81.76 ng/µL). Rutin, hesperidin, neohesperidin, vanillic acid, and p-coumaric acid were detected in lower concentrations. The results indicate that sumac extracts are among the natural antioxidant sources with high phenolic content. The presence of phenolic compounds reveals that the sumac plant plays an effective role in combating oxidative stress, cell regeneration, and suppressing microbial activity. Compounds such as gallic and ferulic acids, in particular, can be evaluated as natural active agents in the cosmetics industry due to their anti-aging, UV-protective, and collagen synthesis-supporting properties. Furthermore, sumac extracts can be used as natural preservatives and flavorings in food products; thanks to their antimicrobial properties, they extend shelf life and increase product stability. In the health sector, due to their antioxidant and metabolic balancing effects, they can be considered as a potential raw material in phytotherapeutic formulations. These findings demonstrate that Rhus coriaria is a rich source of phytochemicals in terms of biologically active components and can be a strategic raw material in sustainable production, natural cosmetic formulations, and functional food development processes. Considering Turkey's climatic advantages, the study also reveals the potential of sumac to create economic added value through domestic production.
The authors would like to express their sincere gratitude to Iğdır University Research Application and Analysis Laboratory (ALUM) for providing technical infrastructure and analytical support during the HPLC-DAD analyses. The authors also thank Mardin Artuklu University and Dicle University for their institutional support and contributions to the successful completion of this research.
This study did not involve human participants or experimental animals. The plant material (Rhus coriaria L.) used in the research was obtained from commercially available sources and/or collected in compliance with national and institutional regulations governing the collection and use of plant resources in Turkey. All experimental procedures were conducted in accordance with internationally accepted ethical standards for laboratory research, ensuring scientific integrity, data accuracy, and reproducibility. The authors confirm that no ethical approval was required for this study.
This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.
The authors declare that there are no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Al-Snafi A. E. (2015) Chemical constituents and pharmacological effects of Rhus coriaria – A review. International Journal of Pharmacy and Pharmaceutical Sciences, 7(9): 12–20.
Aras A., Karadağ M. (2024) Bazı bitkilerin sekonder metabolit içeriklerinin HPLC ile analizi. Journal of Agriculture, 7(2): 157-167.
Bagheri S. et al. (2020) Antioxidant and antimicrobial activities of Rhus coriaria extracts: A comprehensive review. Food Science and Nutrition, 8(4): 1732–1745.
Başar Y., Gül F., Karadağ M., Alma M.H., Demirtas I., Tel A.Z. (2024) Determination of the volatile, phenolic and fatty acid contents of Helichrysum plicatum by chromatographic methods. Turkish Journal of Biodiversity, 7(2): 83-94.
Ekor M. et al. (2020) Medicinal and aromatic plants: Industrial applications and global perspectives. Journal of Herbal Medicine, 22: 100-110.
Karadag M., Doğan S. (2024) Mask for moisturizing skin and body made from cold-pressed paste of peanuts (Arachis hypogaea L.). Adv. Biol. Earth. Sci., 9(1): 155-60.
Karadag M., Baran A., Güneş Z. (2024) Production of value-added cosmetic products from cold-pressed Helianthus annuus L. oil and pulp. Advances in Biology & Earth Sciences, 9(Special Issue): 35-39.
Karadağ M. (2025) Mentha arvensis L.(Kır Nanesi) örneklerinin fenolik bileşik profili. Türkiye Teknik Bilimler ve İnovasyon Dergisi, 1(1): 12-23.
Karadağ M., Omarova S. (2024) Use of Prunus armeniaca L. seed oil and pulp in health and cosmetic products. Adv. Biol. Earth. Sci., 9(1): 105-10.
Karadağ M., Güneş Z., Çelik S. (2025) Iğdır’da yetişen biberiye (Rosmarinus officinalis L.) bitkisinden elde edilen uçucu yağın kimyasal kompozisyonu ve kozmetik alanındaki kullanımı. Journal of Agriculture, 8(1): 53-64.
Karadağ M., Koyuncu M., Atalar M.N., Aras A. (2021) SPME/GC-MS analysis of Artemisia campestris subsp. glutinosa, Lavandula angustifolia Mill., and Zingiber officinale volatiles. Erzincan Üniversitesi Fen Bilim Enstitüsü Derg., 14: 41-49.
Koçak M.Z., Karadağ M., Çelikcan F. (2021) Essential oil composition of Salvia officinalis and Rosmarinus officinalis. Journal of Agriculture, 4(1): 39-47.
Mehdizadeh L. et al. (2016) Phytochemical and pharmacological properties of sumac (Rhus coriaria): A review. Journal of Medicinal Plants Research, 10(11): 155–163.
Zhang N., Baran A., Valioglu F., Teng L., Atalar M.N., Keskin C., ... Beilerli A. (2023) Antioxidant, AChE inhibitory, and anticancer effects of Verbascum thapsus extract. Cellular and Molecular Biology, 69(14): 211-216.
Received: November 18, 2025; Reviewed: December 11, 2025; Accepted: December 18, 2025
DOI:
https://doi.org/10.62088/timbb/9.2.10Keywords:
Rhus coriaria, phenolic compounds, HPLC-DAD, antioxidant activity, cosmetic applications, functional foods
Karadag, M., Baran, M., Aslan, K., Adican, M.. (2025). THE USE OF SUMAC (RHUS CORIARIA) PLANT IN VALUE-ADDED COSMETIC, HEALTH AND FOOD PRODUCTS. TIMBB, 9 (2), 79-84.